PCF ® Process Development

/PCF ® Process Development
PCF ® Process Development2018-10-12T04:52:28+00:00

Comprehensive Supply Solutions via PCF®

Phyton Biotech’s unique state-of-the-art capabilities and impressive history of expertise in development and production enable us to carry out each and every step required for a full development program — from first plant cell to scale-up.

We offer comprehensive development services for the development and commercialization of high-value plant-based compounds using our patented Plant Cell Fermentation (PCF®) Technology, serving the pharmaceutical, Traditional Chinese Medicine (TCM), cosmetic, agricultural and food ingredient industries. Phyton has unique capabilities to address the entire development chain for the development, production and commercialization of complex small molecules, and plant-based actives and recombinant proteins. Our wide range of world-class development solutions include:

Phyton Biotech Infographic on Paclitaxel and Docetaxel

Biological & Technical Feasibility

  • Feasibility – assess whether plant-based molecule appropriate to be produced via PCF®

  • Sourcing of plant material – from natural sources

  • Selection of plant material – select and use the best natural cell factories from the target plant

  • Cell line development – identify and create high-producing cell line, including cryopreservation of target plant cells, as appropriate
  • Fermentation/DSP development – one viable cell as starting material serves for tons of product

Process Development & Scale-Up

  • Semi-synthesis – as applicable, semi-synthesis process used on plant-based molecules to generate the target molecules
  • Scale-up – capable of developing processes to scale up to commercial production capacity
  • Small to large-scale commercial production – produce products from small-to-commercial scale, as needed
  • Purification capabilities
  • Analytical methods development capabilities

Up/Downstream Production

  • Full project management – capable of providing full project management support, from R&D to commercial launch
  • Regulatory support capabilities
  • Analytical testing capabilities

Custom process development

Our team of experts at Phyton Germany can develop new processes for clients for a variety of complex plant-based molecules. Based on our significant experience working with phytochemicals using our award-winning (PCF®) platform, Phyton is capable of developing custom processes to meet the needs of clients across the pharmaceutical, Traditional Chinese Medicine (TCM), cosmetic, agricultural and food ingredient industries.

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Custom product manufacturing

Our team of experts can assist clients with the development and commercialization of their products in development, from scale up to analytical testing, regulatory filing and beyond. Based on our significant experience working with phytochemicals using our award-winning PCF® platform, Phyton is capable of developing custom product manufacturing solutions to meet the needs of clients across the pharmaceutical, Traditional Chinese Medicine (TCM), cosmetic, agricultural and food ingredient industries.

Contact Us About Partnering Opportunities

Download our brochure on supply solutions via PCF®

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